Emerging Viral Infections

Led by: Simona RUTA
Fields: Medicine and pharmaceutics
Institution: „Ştefan S. Nicolau” Institute of Virology
Scientists/Total: 7/7
Keywords:  Infections; Epidemics; Pathology.

Pediatric HIV infection:
1. virological and immunological monitoring of long term survivor HIV parenterally infected children;
2. virological studies in the pediatric AIDS encephalopathy
3. surveillance of the antigenic heterogeneity of the circulating viral strains
4. sero/genotyping the HIV isolates from nonprogressors and recently infected adults or vertically infected children in order to understand resistance development and the corresponding changes in viral fitness on a molecular level;
5. evaluation of HIV-specific immunity in infected children who were subjects of non-structured interruptions of treatment;
6. investigation of the natural history of HBV and HCV coinfections in HIV infected children;
7. molecular diagnosis in malignant opportunistic diseases involving EBV, HPV and HHV8 in HIV infected individuals
Parenterally acquired viral hepatitis:
1. serosurveillance studies for HBV, HCV and HDV in the general population and in selected risk groups directed to the identification of virus transmission routes and infection sources;
2. evaluation of HBV and HCV genotypes/viral isolates circulating in Romania
3. assessing the  the impact of genetical diversity on the performance of diagnostic tests used in clinical laboratories and developing methods that allow identification and characterization of new HCV subtypes/isolates and recombinants strains with high pathogenity risk
The early warning and control of viral epidemics.





Şos. Mihai Bravu nr. 285, Sector 3, 030304
Municipiul București, România
Tel: +40 21 3242590
Fax: +40 21 3242590
eMail: simo...@yahoo.com




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