Viral Glycoproteins

Led by: Norica NICHITA
Fields: Medicine and pharmaceutics
Molec. Cell. & Sys. Biol.
Institution: Institute of Biochemistry
Scientists/Total: 4/4
Keywords:  molecular biology, glycoprotein folding, viral envelope packing, lipid metabolism, viral and subviral particles assembly, HBV, HCV
Presentation

The Viral Glycoproteins group was founded in 2002 with the aim to apply the methods developed in the Institute for the study of glycoprotein folding, to a more specific but highly challenging field of molecular biology . the viral envelope packing. The group works in collaboration with the Molecular Cell Biology group and also with colleagues from the Department of Biochemistry, University of Oxford, UK and the University of Lyon, France.
In the next years our group will extend the research on the HBV life cycle by studying the role of the lipid metabolism in the viral and subviral particles assembly.

Infrastructures

Cell Culture
- Flow cytometer
- Sterile hoods
- Fluorescence microscope
- CO2 incubators
- Inversion microscope
- Freezers (-80 OC)
- Ultracentrifuge
- Refrigerated centrifuges

Molecular Biology
- PCR & RT-PCR
- Spectrophotometer
- DNA electrophoresis
- UV transiluminator
- Refrigerated centrifuges
- Bench-top centrifuges
- Electroporator
- Sonicator
- Sterile hoods

Analytical & Preparative Biochemistry
- 1D- & 2D electrophoresis
- Scintilator
- HPLC
- FPLC
- ELISA
- Spectrophotometers
- Vacuum systems
- GelDoc

Crystallography
- PX Scanner Difractometer
- Microscope

Bioinformatics & Molecular Modelling
- Silicon Graphics Workstation
- Clusters for Parallel Computing
- Insight II Software
- CHARMm & Amber
- Structural Databases
- SAGS

Applications

Development of novel antiviral strategies against Hepatitis B and C viruses.

Contact

Splaiul Independenţei nr. 296, Sector 6, 060031
Municipiul București, România
Tel: +40 21 2239069
Fax: +40 21 2239068
eMail: nich...@biochim.ro

 

 

 

0 Patents or Software

 

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